PANSS Scale

Assess the baseline function and treatment responses of patients with schizophrenia and psychosis with the PANSS scale.

By Patricia Buenaventura on Jul 17, 2024.

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Fact Checked by Nate Lacson.

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What is the Positive and Negative Syndrome Scale (PANSS)?

The Positive and Negative Syndrome Scale, or PANSS, is a widely utilized medical instrument designed to measure symptom severity in individuals with schizophrenia and other disorders, such as psychosis. This scale, adapted from parts of the Brief Psychiatric Rating Scale and Brief Rating Scale, serves as a comprehensive tool for assessing the positive and negative symptoms associated with the disorder.

The scale has three parts which are:

  • Positive scale: This component measures 7 symptoms that signify an excess or distortion of normal functions. The items evaluated under this scale include delusions, conceptual disorganization, hallucinations, excitement, grandiosity, suspiciousness/persecution, and hostility.
  • Negative scale: This component assesses 7 symptoms indicative of a diminution or loss of normal functions. The items measured are blunted affect, emotional withdrawal, poor rapport, passive/apathetic social withdrawal, difficulty in abstract thinking, stereotype thinking, and lack of spontaneity and flow of conversation.
  • General psychopathology scale: This scale contains 16 items and evaluates a broader range of symptoms, including anxiety, depression, motor retardation, etc.

The PANSS is extensively employed in the research and evaluation of antipsychotic therapies. Its robust structure and comprehensive assessment capability make it an invaluable tool in clinical trials, research settings, and others. It facilitates a nuanced understanding of symptomatology in schizophrenia and guides therapeutic interventions.

Currently, however, the search for a consensus five-factor model in PANSS for schizophrenia is being done to identify subtle item combinations that transcend traditional symptom categories, thereby enabling better treatment allocation for individual patients. Furthermore, for research, healthcare professionals are constantly testing out reliable and valid PANSS factor structures through exploratory and confirmatory factor analyses to assess symptom dimensions accurately.

How to use our PANSS Scale template

The Positive and Negative Syndrome Scale is an essential tool in assessing the severity of schizophrenia symptoms. Following a structured process when using the PANSS Scale template is important to ensure accurate and reliable results. Below is a step-by-step guide you can use to make the most out of our template:

Step 1: Prepare beforehand

Click on the "Download Template" or "Use Template" button in this guide to grab a copy of the PANSS scale and familiarize yourself with its content. Afterward, arrange the setting for the test/interview and obtain informed consent from the patient.

Step 2: Complete the test

Follow the structure provided on the template, systemically addressing each item on the PANSS. Ensure that you cover the three main scales: the positive scale, the negative scale, and the general psychopathology scale.

Step 3: Score and interpret

Once the patient has answered all items, proceed to score by following the scoring system provided in this guide. Afterward, you can calculate the total score by adding the scores on each scale and obtaining the sum of the scores on the three scales for the overall total score.

After obtaining the overall score, interpret it within the context of the patient’s clinical history and current presentation. Generally, higher scores indicate greater severity of symptoms.

Step 4: Next steps

Use the scores to guide clinical decisions and adjust treatment, medication, and interventions accordingly. Don't forget to provide feedback to the patients explaining the results, document the outcome in the patient's medical record, and schedule a follow-up for monitoring.

PANSS Scale scoring

The PANSS is an essential tool for evaluating symptom severity in patients with schizophrenia. The scoring process is meticulous, ensuring a comprehensive assessment of positive and negative syndromes through a structured clinical interview. Here is an overview of what to keep in mind regarding scoring:

  • Each item is rated from 1 to 7, with 1 indicating the absence of symptoms and 7 representing extreme symptomatology. Note that each rating reflects increasing levels of symptom severity.
  • Assign the highest applicable rating point to capture the most severe manifestation accurately.
  • The positive and negative scales have potential score ranges of 7 to 49, while the general psychopathology scale has a rating from 16 to 112.  
  • Depressive symptoms may manifest differently in psychopathologically heterogeneous samples and may require additional clinical measures.

PANSS Scale interpretation

The PANSS is an essential tool for evaluating the symptom severity in patients with schizophrenia. The scores obtained from the PANSS provide comprehensive insights into the various dimensions of the disorder. Here is a detailed guide on how to interpret these scores:

  • Positive scale: Higher scores on the Positive Scale indicate more severe positive symptoms. Clinicians use this score to evaluate the efficacy of treatments targeting these productive symptoms and to monitor changes over time.
  • Negative scale: Higher scores on the Negative Scale reflect more severe negative symptoms. Negative symptoms are often persistent and can severely impact the patient’s quality of life. Understanding the severity of these symptoms helps tailor interventions to improve social functioning and emotional responsiveness.
  • General psychopathology scale: Higher scores on the General Psychopathology Scale indicate a broader range of psychopathological symptoms. This comprehensive assessment helps in identifying co-occurring conditions and the overall severity of the patient’s mental health state.

Next steps after using PANSS

After completing, scoring, and interpreting the PANSS Scale, clinicians undertake critical steps to ensure effective and individualized patient care. The following are possible steps healthcare professionals may take after conducting the scale:

  • Tailored treatment plans: Based on the PANSS scores, clinicians develop personalized treatment plans to address the specific symptoms identified during the assessment. These may include antipsychotic medications and psychosocial interventions such as CBT and other types of therapy.
  • Follow-up assessments and treatment adjustments: Regular follow-up assessments using the PANSS are essential to tracking changes in symptom severity over time. Based on the assessments' outcomes, healthcare professionals can make necessary adjustments to the treatment plan, such as modifying medication dosages, introducing new therapeutic interventions, or discontinuing ineffective treatments.
  • Offering a holistic approach: In addition to managing the patient's psychiatric symptoms, the overall well-being must also be taken care of. To do so, clinicians may target physical health, encourage the patient to engage in social activities, provide emotional support, teach coping strategies, and educate the patient and the family on schizophrenia, its symptoms, etc.
What is the reliability and validity of the PANSS scale?
What is the reliability and validity of the PANSS scale?

Commonly asked questions

What is the reliability and validity of the PANSS scale?

The PANSS scale has high test-retest reliability and is considered a valid instrument for assessing the severity of schizophrenia symptoms. Exploratory factor analysis (EFA) is often conducted to ascertain the factor structure of psychopathology in a sample population, which helps validate the scale.

What is the 5-factor model of the PANSS?

The five-factor model or solution organizes the PANSS factors according to the following: positive symptoms, negative symptoms, disorganization/cognitive, depression/anxiety, and hostility.

Does PANSS diagnose schizophrenia?

It is one of the tools to diagnose schizophrenia. However, it is not the only one that should be used.

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