Macrocytosis ICD-10-CM Codes

What ICD-10 Codes are Used for Macrocytosis?

Macrocytosis refers to the presence of larger than normal red blood cells, often seen in blood tests. While it can be an indication of a variety of medical conditions, its accurate coding is vital for patient care, research, and medical billing. The ICD-10-CM offers standardized codes for this hematological finding.

Commonly Used ICD-10-CM Codes for Macrocytosis:

D75.81 - Primary polycythemia

A condition where the body produces too many red blood cells, leading to increased blood volume and viscosity.

D75.82 - Secondary polycythemia

Similar to primary polycythemia, but as a response to another condition like chronic hypoxia or tumors secreting erythropoietin.

R71.0 - Polycythemia vera

A type of blood cancer where the bone marrow produces too many red blood cells.

R71.1 - Excessive erythrocytosis

An increase in the number of red blood cells in the blood, which can lead to blood thickening.

‍(Note: Macrocytosis, as a descriptive term for larger red blood cells, is often a laboratory finding and might not always have a direct ICD-10-CM code. The physician would code for the underlying condition causing the macrocytosis.)

Which Macrocytosis ICD codes are Billable?

• D75.81 - Yes
• D75.82 - Yes
• R71.0 - Yes
• R71.1 - Yes

Clinical Information

• Macrocytosis denotes the presence of enlarged red blood cells (RBCs) without an increase in the number of RBCs.
• Often detected during a complete blood count (CBC) test.
• Potential causes include vitamin B12 or folic acid deficiency, alcohol consumption, certain medications, liver disease, and bone marrow disorders.
• Macrocytosis can be a sign of megaloblastic anemia, where the bone marrow produces fewer, but larger RBCs.
• Treatment and management depend on identifying and addressing the underlying cause of macrocytosis.

Synonyms Include:

• Megalocytic anemia
• Macrocytic anemia
• Large red blood cell disorder
• Enlarged erythrocytes
• RBC macrocytosis