Sickle Cell Disease ICD-10-CM Codes

Simplify coding with our comprehensive list of ICD-10 Codes Used for Sickle Cell Disease. Stay informed and streamline medical coding practices efficiently. 

By Wynona Jugueta on Jun 16, 2024.

Fact Checked by RJ Gumban.

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Sickle Cell Disease ICD-10-CM Codes

What ICD-10 Codes are Used for Sickle Cell Disease 

These Sickle Cell Disease ICD Codes classify different aspects, including anemia, traits, specific genetic combinations, and variations. 

D57

Sickle-cell disorders, primarily sickle cell anemia (or sickle cell disease), are genetic ailments arising from a mutation in the hemoglobin gene. This mutation gives rise to abnormal hemoglobin called hemoglobin S (HbS). Under deoxygenated conditions, HbS causes red blood cells to become inflexible and assume a characteristic sickle or crescent shape. 

D57.1

Unlike sickle cell anemia, this trait generally doesn't cause severe complications, but slight risks like exertional rhabdomyolysis may be present. This code covers the sickle-cell trait, a genetic condition where an individual carries one normal hemoglobin gene (HbA) and one sickle hemoglobin gene (HbS). 

D57.2

Characterized by the inheritance of two distinct abnormal hemoglobin genes, resulting in the combination of different gene variants. This unique genetic makeup can lead to various symptoms and clinical presentations.

D57.8

Encompasses a diverse group of sickle-cell disorders that extend beyond the common sickle-cell anemia. These disorders may involve combinations of abnormal hemoglobin genes, leading to distinct clinical characteristics.

D57.81

Occurs when an individual inherits sickle hemoglobin (HbS) and hemoglobin C (Hb-C) genes. This combination gives rise to a unique set of clinical manifestations, which may differ from other types of sickle cell disorders.

D57.89

Covers specific sickle cell disorders that have distinct features but do not fit precisely into other predefined categories. This code accounts for various less common variations and subtypes of sickle cell conditions.

Which Sickle Cell Disease ICD codes are Billable?

Navigating medical billing and coding requires a clear understanding of which Sickle Cell Disease ICD codes are billable. Here are the billability status of the mentioned codes:

D57- Yes

D57.1 - Yes

D57.2 - No

D57.8 - No

D57.81 - No

D57.89 - No

Clinical Information:

  • Sickle cell disease is a genetic blood disorder.
  • The primary type is sickle cell anemia, causing abnormal hemoglobin in red blood cells.
  • Sickle cells are rigid and can block blood vessels.
  • Normal red blood cells are flexible and move easily through vessels.
  • Complications include:

Anemia: Insufficient healthy red blood cells for oxygen transport.

Infections: Ruptured sickle cells release bacteria into the bloodstream.

Stroke: Blocked blood flow to the brain.

Organ damage: Sickle cells harm lungs, kidneys, liver, and other organs.

  • Treatments encompass:

Pain relief during sickle cell crises with medication.

Replacing sickle cells with healthy ones through blood transfusions.

Lowering infection risk with specific medications.

Curative, but risky, bone marrow transplant from a healthy donor.

  • Though not curable, effective management of sickle cell disease is possible.
  • With proper care, individuals with sickle cell disease can lead long and healthy lives.

Synonyms Include:

  • Drepanocytosis
  • Hemoglobinopathy
  • Hemolytic anemia
  • Sickle cell anemia
  • Sickle cell trait
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Commonly asked questions

When to use a Sickle Cell Disease ICD code?

Use these codes to classify and bill for cases of Sickle Cell Disease in medical records.

What are the common treatments for Sickle Cell Disease Diagnosis Codes?

Treatments may include pain relief, blood transfusions, infection prevention, and, in rare cases, bone marrow transplants.

What does a diagnosis code for Sickle Cell Disease mean?

It's a standardized way to identify and categorize Sickle Cell Disease in medical documentation and billing systems.

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