Sjogren's Syndrome ICD-10-CM Codes | 2023

What ICD-10 Codes are Used for Sjogren's Syndrome?

Sjogren's Syndrome, an autoimmune disorder primarily affecting the exocrine glands, is categorized under several ICD-10 codes depending on the organs involved. Below is a refined list of these codes with enhanced clinical descriptions:

• M35.00 - Sjogren's syndrome, unspecified: This code is applied when a patient is diagnosed with Sjogren's Syndrome but the specific organ involvement is not detailed in the documentation.
• M35.01 - Sjogren's syndrome with keratoconjunctivitis: Indicates Sjogren's Syndrome with ocular involvement, characterized by dryness of the eyes (keratoconjunctivitis sicca) due to lymphocytic infiltration of lacrimal glands.
• M35.02 - Sjogren's syndrome with lung involvement: Used when Sjogren's Syndrome manifests with pulmonary complications, which may include interstitial lung disease or other pulmonary function impairments.
• M35.03 - Sjogren's syndrome with myopathy: Assigned to cases where Sjogren's Syndrome presents with muscle involvement, leading to symptoms such as muscle weakness and pain.
• M35.04 - Sjogren's syndrome with nervous system involvement: Applicable for neurological complications associated with Sjogren's Syndrome, which can range from peripheral neuropathy to central nervous system manifestations.
• M35.09 - Sjogren's syndrome with other organ involvement: This code is reserved for instances where Sjogren's Syndrome affects organs other than those specified in codes M35.01 to M35.04, such as the kidneys, liver, or pancreas.

For a visual and comprehensive explanation of how to apply these ICD-10 codes in clinical documentation, please view our explainer video on Sjogren's Syndrome ICD Codes.

Which Sjogren's Syndrome ICD codes are Billable?

• M35.00 - Yes
• M35.01 - Yes
• M35.02 - Yes
• M35.03 - Yes
• M35.04 - Yes
• M35.09 - Yes

Clinical Information

• Sjogren's Syndrome is a systemic autoimmune condition with hallmark symptoms and various systemic manifestations.
• Persistent dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia) due to the destruction of salivary and lacrimal glands by autoimmune processes.

• Dryness can lead to complications such as dental caries, oral candidiasis, and corneal ulceration.
• May present with extra glandular involvement such as arthralgia, arthritis, and myalgia, contributing to joint pain and swelling.
• Fatigue and myalgia are common, significantly impacting the quality of life.
• Blood tests reveal specific autoantibodies (e.g., Anti-SSA/Ro and Anti-SSB/La). Schirmer's test and other ocular tests are used to assess tear production.
• Salivary gland biopsy may be performed to detect lymphocytic infiltration indicative of the syndrome.
• Symptomatic treatment includes artificial tears, saliva substitutes, and saliva stimulants to alleviate dryness.
• Systemic immunosuppressive therapy may be indicated for patients with severe extra glandular manifestations.
• Regular dental check-ups and oral hygiene are crucial due to the increased risk of dental problems.
• Regular monitoring for the development of systemic complications such as interstitial lung disease, renal tubular acidosis, and lymphoma.
• Follow-up with rheumatology for systemic disease management and with ophthalmology for ocular care.

Synonyms Include:

• Sicca syndrome
• Autoimmune exocrinopathy
• Glandular disease, Sjogren's
• Lymphocytic sialadenitis
• Keratoconjunctivitis sicca