Lisinopril Allergy ICD-10-CM Codes | 2023

What ICD-10 codes are used for Lisinopril allergy?

Lisinopril, a widely prescribed angiotensin-converting enzyme (ACE) inhibitor, is instrumental in managing hypertension and heart failure. However, like all medications, Lisinopril can trigger allergic reactions in some patients. 

The ICD-10-CM coding system facilitates healthcare professionals in systematically documenting and categorizing allergic reactions to Lisinopril. Here's a closer look at the pertinent codes:

• Z88.8: Allergy status to other drugs, medicaments, and biological substances: This code encompasses patients with documented allergies to drugs or biological substances not explicitly mentioned elsewhere. It's a broad category that can include many drug allergies, including those to Lisinopril.
• T46.4X5A: Adverse effect of angiotensin-converting-enzyme inhibitors, initial encounter: This code is specifically tailored for patients who manifest adverse reactions to ACE inhibitors, such as Lisinopril, during their initial medical encounter. It captures the immediate allergic responses that might arise shortly after the drug's administration.

Which Lisinopril allergy ICD codes are billable?

• Z88.8: Yes
• T46.4X5A: Yes

Clinical information

Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor primarily prescribed to manage hypertension and heart failure.

Allergic reactions

• Allergic responses to Lisinopril can manifest in various ways, from mild skin reactions to life-threatening conditions.
• Common symptoms include allergic rhinitis, rashes, itching, and hives.
• More severe reactions can lead to angioedema, characterized by deep tissue swelling, often around the eyes, lips, and sometimes the throat.
• In rare cases, patients might experience difficulty breathing due to swelling in the respiratory tract.

Management and treatment

• Any suspected drug reaction to Lisinopril requires immediate medical evaluation.
• Emergency care is essential for severe reactions, especially respiratory distress or significant swelling.
• If an allergy to Lisinopril is diagnosed, healthcare providers will typically discontinue the medication.
• Alternative antihypertensive medications can be considered, ensuring they don't belong to the ACE inhibitor class to prevent cross-reactivity.

Prevention and monitoring

• Patients with known allergies to ACE inhibitors should inform their healthcare providers. In addition, any risk factors and factors influencing health status may also be mentioned to the provider.
• Regular monitoring and follow-up are crucial to detect and manage potential allergic reactions early, especially when starting a new medication.

Synonyms include

• Lisinopril hypersensitivity
• ACE inhibitor allergy
• Angioedema due to Lisinopril
• Lisinopril-induced rash
• Adverse reaction to Lisinopril